Climate change exacerbates the existing challenges to food security in the Middle East and North Africa region. Challenges include water scarcity, increasing population, economic slowdown, global crisis as COVID-19, and Russo-Ukrainian war. The present paper aims to contribute to the existing literature tackling climate effects on food security in the region. The paper investigates the impact of climate on food access and food utilization, using panel data for 12 MENA countries during the period from 2000 to 2020. The findings show that GHG emissions and changes in surface temperature negatively affects food access in the region by increasing the number of undernourished. However, food utilization, measured by the prevalence of stunting among children under five years older, is not affected by the used climate indicators. Moreover, the main drivers of food security in the MENA region include inflation, urbanization and access to sanitation. The findings are policy relevant. Policies and intervention programs should differ according to the targeted dimensions of food security. Adaptation and mitigation strategies are required to ensure food security and environmental sustainability.